ES8107191A1 - Procedimiento para la preparacion de 2-(2-cloro-4-ciclopro- pil-fenil-imino)-imidazolidina - Google Patents
Procedimiento para la preparacion de 2-(2-cloro-4-ciclopro- pil-fenil-imino)-imidazolidinaInfo
- Publication number
- ES8107191A1 ES8107191A1 ES494417A ES494417A ES8107191A1 ES 8107191 A1 ES8107191 A1 ES 8107191A1 ES 494417 A ES494417 A ES 494417A ES 494417 A ES494417 A ES 494417A ES 8107191 A1 ES8107191 A1 ES 8107191A1
- Authority
- ES
- Spain
- Prior art keywords
- cyclopropyl
- chloro
- phenyl
- imino
- acid addition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 2
- NJGRRCIKURPQPP-UHFFFAOYSA-N n-(2-chloro-4-cyclopropylphenyl)-4,5-dihydro-1h-imidazol-2-amine Chemical compound ClC1=CC(C2CC2)=CC=C1NC1=NCCN1 NJGRRCIKURPQPP-UHFFFAOYSA-N 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- VIDYWXHUSODKFC-UHFFFAOYSA-N (2-chloro-4-cyclopropylphenyl)urea Chemical compound C1=C(Cl)C(NC(=O)N)=CC=C1C1CC1 VIDYWXHUSODKFC-UHFFFAOYSA-N 0.000 abstract 1
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical class NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000029078 coronary artery disease Diseases 0.000 abstract 1
- 230000001121 heart beat frequency Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/30—Isothioureas
- C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Seasonings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792933930 DE2933930A1 (de) | 1979-08-22 | 1979-08-22 | 2-(2-chlor-4-cyclopropyl-phenylimino)-imidazolidin, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES494417A0 ES494417A0 (es) | 1981-08-16 |
| ES8107191A1 true ES8107191A1 (es) | 1981-08-16 |
Family
ID=6079013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES494417A Expired ES8107191A1 (es) | 1979-08-22 | 1980-08-21 | Procedimiento para la preparacion de 2-(2-cloro-4-ciclopro- pil-fenil-imino)-imidazolidina |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4341788A (en]) |
| EP (2) | EP0024673B1 (en]) |
| JP (1) | JPS56501087A (en]) |
| AT (1) | ATE4204T1 (en]) |
| BG (1) | BG33281A3 (en]) |
| CS (1) | CS212724B2 (en]) |
| DD (1) | DD152783A5 (en]) |
| DE (2) | DE2933930A1 (en]) |
| DK (1) | DK157381A (en]) |
| ES (1) | ES8107191A1 (en]) |
| FI (1) | FI68815C (en]) |
| GR (1) | GR69874B (en]) |
| HU (1) | HU181790B (en]) |
| IE (1) | IE50114B1 (en]) |
| NO (1) | NO150118C (en]) |
| PT (1) | PT71725B (en]) |
| RO (1) | RO82161A (en]) |
| SU (1) | SU1021341A3 (en]) |
| WO (1) | WO1981000565A1 (en]) |
| YU (1) | YU211180A (en]) |
| ZA (1) | ZA805201B (en]) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7711390A (nl) * | 1977-10-18 | 1979-04-20 | Philips Nv | Nieuwe 2-arylimino-hexahydopyrimidinen en - imi- dazolidinen, zouten en complexen daarvan, werk- wijze ter bereiding van de nieuwe verbindingen, alsmede fungicide preparaten op basis van de nieuwe verbindingen. |
| HU192986B (en) * | 1984-05-23 | 1987-08-28 | Egyt Gyogyszervegyeszeti Gyar | Process for production of imidasodiline derivatives |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA462824A (en) * | 1950-01-31 | Frank Short Wallace | Manufacture of heterocyclic amines | |
| BE632578A (en]) * | 1963-05-22 | |||
| NL7711390A (nl) * | 1977-10-18 | 1979-04-20 | Philips Nv | Nieuwe 2-arylimino-hexahydopyrimidinen en - imi- dazolidinen, zouten en complexen daarvan, werk- wijze ter bereiding van de nieuwe verbindingen, alsmede fungicide preparaten op basis van de nieuwe verbindingen. |
| DE2831234A1 (de) * | 1978-07-15 | 1980-01-31 | Boehringer Sohn Ingelheim | Neue substituierte 2-phenylamino-imidazoline-(2) deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben |
| DE2854659A1 (de) * | 1978-12-18 | 1980-07-10 | Boehringer Sohn Ingelheim | Neue 3,4-disubstituierte 2-phenylimino-imidazolidine, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung |
| US4290971A (en) * | 1979-01-19 | 1981-09-22 | Dso "Pharmachim" | Method of preparing 2-(phenylamino)-imidazolines-(2) |
-
1979
- 1979-08-22 DE DE19792933930 patent/DE2933930A1/de not_active Withdrawn
-
1980
- 1980-08-19 EP EP80104917A patent/EP0024673B1/de not_active Expired
- 1980-08-20 HU HU801056A patent/HU181790B/hu unknown
- 1980-08-20 DE DE8080901722T patent/DE3064276D1/de not_active Expired
- 1980-08-20 WO PCT/EP1980/000081 patent/WO1981000565A1/de active IP Right Grant
- 1980-08-20 RO RO80104087A patent/RO82161A/ro unknown
- 1980-08-20 US US06/253,860 patent/US4341788A/en not_active Expired - Fee Related
- 1980-08-20 JP JP50203780A patent/JPS56501087A/ja active Pending
- 1980-08-20 AT AT80901722T patent/ATE4204T1/de not_active IP Right Cessation
- 1980-08-21 ES ES494417A patent/ES8107191A1/es not_active Expired
- 1980-08-22 BG BG048913A patent/BG33281A3/xx unknown
- 1980-08-22 CS CS805760A patent/CS212724B2/cs unknown
- 1980-08-22 PT PT71725A patent/PT71725B/pt unknown
- 1980-08-22 GR GR62724A patent/GR69874B/el unknown
- 1980-08-22 DD DD80223464A patent/DD152783A5/de unknown
- 1980-08-22 FI FI802651A patent/FI68815C/fi not_active IP Right Cessation
- 1980-08-22 IE IE1785/80A patent/IE50114B1/en unknown
- 1980-08-22 ZA ZA00805201A patent/ZA805201B/xx unknown
- 1980-08-25 YU YU02111/80A patent/YU211180A/xx unknown
-
1981
- 1981-03-09 EP EP80901722A patent/EP0034623B1/de not_active Expired
- 1981-04-03 NO NO811156A patent/NO150118C/no unknown
- 1981-04-07 DK DK157381A patent/DK157381A/da not_active IP Right Cessation
- 1981-04-21 SU SU813272152A patent/SU1021341A3/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| HU181790B (en) | 1983-11-28 |
| RO82161B (ro) | 1983-06-30 |
| DK157381A (da) | 1981-04-07 |
| US4341788A (en) | 1982-07-27 |
| YU211180A (en) | 1983-06-30 |
| IE801785L (en) | 1981-02-22 |
| FI68815C (fi) | 1985-11-11 |
| RO82161A (ro) | 1983-07-07 |
| ES494417A0 (es) | 1981-08-16 |
| BG33281A3 (bg) | 1983-01-14 |
| NO150118B (no) | 1984-05-14 |
| GR69874B (en]) | 1982-07-20 |
| SU1021341A3 (ru) | 1983-05-30 |
| PT71725B (pt) | 1982-01-26 |
| DE3064276D1 (en) | 1983-08-25 |
| JPS56501087A (en]) | 1981-08-06 |
| FI802651A7 (fi) | 1981-02-23 |
| DE2933930A1 (de) | 1981-03-12 |
| EP0024673B1 (de) | 1983-07-20 |
| PT71725A (de) | 1980-09-01 |
| DD152783A5 (de) | 1981-12-09 |
| FI68815B (fi) | 1985-07-31 |
| ATE4204T1 (de) | 1983-08-15 |
| EP0034623B1 (de) | 1983-07-20 |
| ZA805201B (en) | 1982-07-28 |
| WO1981000565A1 (en) | 1981-03-05 |
| NO150118C (no) | 1984-08-22 |
| NO811156L (no) | 1981-04-03 |
| EP0024673A1 (de) | 1981-03-11 |
| IE50114B1 (en) | 1986-02-19 |
| EP0034623A1 (de) | 1981-09-02 |
| CS212724B2 (en) | 1982-03-26 |
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